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Join a Medical Study on Metformin and Aging!

October 8, 2025

In our March 19 post, we highlighted a study exploring the potential of metformin to slow aging. Now, the landmark TAME (Targeting Aging with Metformin) Trial is recruiting adults aged 65–79 to help test whether this trusted diabetes drug can delay or prevent chronic diseases like heart disease, cancer, and dementia. Spanning 14 leading research centers over six years, this is your chance to help redefine how we approach aging itself. Learn more and sign up for updates here.

Midlife Matters: When Your Body’s Clock Speeds Up

September 24, 2025

Our Aug 27 posting describes that aging is not linear—but did you know aging starts to accelerate around age 50? A new study reveals this is when many organs, especially your veins, begin to decline more rapidly, offering a crucial window for mid-life interventions. Researchers say understanding these shifts could help us design better strategies to stay healthier for longer. Learn more.

Healthy aging is not an afterthought—it starts now

September 10, 2025

A new study shows that many anti-aging treatments—such as fasting, healthy eating, and certain medications—are most effective when started earlier in life. As we age, our bodies change, and some treatments may lose their impact. Healthy aging isn’t an afterthought. Take care of your body now—your future self will thank you. Here is the published study.

Aging is not linear—it happens in waves

August 27, 2025

A new study examining human tissues across five decades reveals that aging is not a smooth, linear process. Each organ follows its own rhythm and ages at different times—some accelerate around age 50, others around 80. This wave-like pattern of aging challenges the idea of a universal biological clock. The findings could help identify when and where to intervene to extend healthspan and delay age-related decline. Here is the published study.

Using MRI to measure brain biological age

August 13, 2025

The July 30 post highlighted that the biological age of the brain and immune system are uniquely powerful indicators of longevity. Now, a complementary study by researchers at Duke University and the University of Otago shows that a single MRI scan—using technology already common in hospitals—can predict biological brain aging with surprising accuracy. Here is the published study.

The Two Organs That Best Predict How Long You’ll Live

July 30, 2025

Last week’s post explored how scientists can now estimate the biological age of 11 organs. But not all organs are equal when it comes to predicting lifespan. That same study from Stanford also revealed that the biological age of the brain and immune system are uniquely powerful indicators of longevity. Here is the published study.

Track It to Prevent It

July 23, 2025

Stanford researchers have developed a new blood test that estimates the biological age of individual organs based on protein levels. This tool could become a powerful predictor of health risks—and a guide for early interventions to prolong wellness. Learn more about the test.

Measuring Aging With A Drop of Blood

July 16, 2025

Researchers have developed a fast, affordable test from a single drop of blood or saliva to measure age-related decline. The test measures intrinsic capacity —your combined mental & physical abilities. It could revolutionize how we track aging and personalize interventions. Learn more about the test.

Biological Age - Measuring What Matters

July 9, 2025

Biological age is a better predictor of disease risk, longevity, and overall vitality than your actual age as it is based on health markers like inflammation, sleep, fitness and more. Staying younger on the inside starts with measuring what matters. Learn more about biological age.

Sit-To-Stand – A Simple Longevity Measure

July 2, 2025

A recently released study involving over 4,000 adults shows that a simple sitting-rising test score is a powerful indicator of longevity. Researchers had participants aged 46–75 sit down on the floor and stand back up without support, deducting points for using hands, knees, or wobbling—lower scores correlated with higher mortality over a 12‑year follow‑up. More: details of the study and the video of the test and scoring.

Measure What Matters – The Future of Personalized Longevity

June 25, 2025

A key concept of Medicine 3.0 (see last week's post) is the measurability of health. Just last week, researchers introduced an exciting breakthrough: a simple blood or saliva test that can estimate your biological age and predict your lifespan by measuring “intrinsic capacity.” This new epigenetic clock—called DNAm IC—could revolutionize how we monitor and improve long-term health. Here is the study.

Medicine 3.0

June 18, 2025

With over 1.5 million copies sold, Outlive: The Science and Art of Longevity has been widely recognized as a groundbreaking work on the pursuit of long life and better health. Central to the book is the concept of “Medicine 3.0,” which emphasizes a data-driven approach to optimizing healthspan. By systematically measuring and tracking key health indicators, individuals can better understand their current state and make informed, proactive decisions to enhance their long-term well-being. You can watch a brief interview with him here. The book is available here.

Clinical Trial of Rapamycin and Its Impact on Longevity

June 11, 2025

In our March 19 post, we highlighted a study exploring the potential of Metformin to slow aging. A long-anticipated clinical trial has now concluded that another existing medication: Rapamycin may safely enhance healthspan in older adults. The study involved 114 participants aged 50 to 85 over a 48-week period. Here is the full report.

How Much Exercise to Impact Longevity?

June 04, 2025

How much movement does it take to boost your longevity? A landmark 30-year study following over 116,000 adults found that just 75 minutes of vigorous exercise per week was linked to a 21% increase in long-term health and lifespan. Discover how small, consistent efforts can lead to a stronger, longer, and more vibrant life here.

Virtual Reality and Emotional Well-Being

May 28, 2025

A growing number of care facilities are embracing VR experiences—like virtual museum visits and beach strolls—and studies show they can reduce feelings of isolation by up to 45% in older adults. Learn how immersive technology is transforming emotional well-being and redefining connection for seniors in long-term care here.

Are Video Games Good for Seniors?

May 21, 2025

A recent study published in Brain Sciences found that older adults who engaged in video game training experienced significant improvements in cognitive functions, including memory, attention, and decision-making skills. These findings suggest that incorporating video games into daily routines could be a fun and effective way for seniors to enhance their mental agility. Learn more here.

Digital Devices and Cognitive Health

May 14, 2025

Could your smartphone or tablet be keeping your brain sharp? A comprehensive analysis of 57 studies involving over 411,000 adults aged 50 and above found that regular use of digital devices is associated with a 58% lower risk of cognitive impairment and a 26% reduction in cognitive decline. Learn more here.

Scientific American: Extending Healthspan

May 07, 2025

Discover how cutting-edge science is shifting focus from merely extending lifespan to enhancing healthspan—ensuring more years of vibrant, active living. From promising anti-aging drugs to personalized, data-driven wellness strategies, researchers are making strides in helping people stay mentally sharp and physically robust well into their 90s and beyond. Take a close look at this special edition from Scientific American.